New Stereoselective Synthesis of 4-Butyl-α-agarofuran
摘要
A potent anxiolytic 4-butyl-α-agarofuran (AF-5) was synthesized from (+)dihydro-carvone. Acid catalyzed hydration of (+)dihydrocarvone and interconversion with β-O-ketone 8and the key intermediate α,β-unsaturated ketone 5 made this synthesis more practical.
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Chunli, DaLiYIN, 张晋文, 等. New Stereoselective Synthesis of 4-Butyl-α-agarofuran[J]. 中国化学快报:英文版, 2003.
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