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New Metabolites of Aconitine in Rabbit Urine

HongGuiZHANGXiangGuoSHI

2002中国化学快报:英文版Pharmacology, Toxicology and Pharmaceutics被引 6

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摘要

A sensitive analytical method to identify and determine aconitine and its metabolites in rabbit urine was developed by liquid chromatography-electrospray ionization mass spectometry (LC/ESI-MSn).In this method,aconitine and its four metabolites in rabbit urine were isolated and deduced as 16-O-demethylaconine (M1),benzoylaconine(M2),16-O-demethylbenzoylaconine (M3)and aconie(M4).M1 and new metabolites of aconitine and M2 and M4 are first identified in urine.

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HongGuiZHANG, XiangGuoSHI. New Metabolites of Aconitine in Rabbit Urine[J]. 中国化学快报:英文版, 2002.

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