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Preliminary Study on Cordycepin-DNA Interaction by Raman Spectroscopy

JianYaLINGQinZhengYANGShanShanLUOYanliChangKaiZHANG

2005中国化学快报:英文版Chemistry被引 4

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摘要

The interaction of cordycepin with calf thymus DNA was investigated at physiological pH with drug/DNA molar ratio of 8. The Raman spectroscopy results indicated that the intercalation of high concentration cordycepin and the interaction of cordycepin with PO2 group led to a major reduction of B-form DNA structure in favor of A-form DNA.

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JianYaLING, QinZhengYANG, ShanShanLUO, 等. Preliminary Study on Cordycepin-DNA Interaction by Raman Spectroscopy[J]. 中国化学快报:英文版, 2005.

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