Synthesis and Spectral Characterization of Novel Sulfhydryl-reactive Benzimidazole Fluorescent Probes
摘要
Three sulfhydryl-reactive fluorescent probes, which contain 2-(1H-benzoimidazol-2-yl)-phenol and ma- leimide group, were synthesized and their structures were characterized by IR and 1 H NMR. Their photo-physical properties and the specificity to sulfhydryl group in the 2-mercapto-ethanol as well as the L-cysteine adducts were indicated by fluorescence intensity. Preliminary tests revealed that the probes could react selectively with the cysteine molecules, suggesting that these probes might be generally useful in biomedical researches. Keywords Fluorescent probe; 2-(2-Hydroxyphenyl) benzimidazole; Sulfhydryl-reactive Article ID 1005-9040(2010)-03-402-04
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Ouyang Jie Lei Ying-jie, Ding Mei. Synthesis and Spectral Characterization of Novel Sulfhydryl-reactive Benzimidazole Fluorescent Probes[J]. 未知来源, 2010.
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