Synthesis of 4－Amino－5－furyl－2－yl－4H－1, 2, 4－triazole－3－thiol Derivatives as a Novel Class of Endothelin（ET） Receptor Antagonists
摘要
A series of novel 3-alkylthio-4-arylideneamino-5-(2-furyl)-1, 2, 4-triazole derivatives were synthesized. Their chemical structures were confirmed with elemental analysis and spectral data. Endothelin(ET) receptor competitive binding assay showed that some compounds exhibited high selective as potent ET-1 receptor antagonist.
引用本文（GB/T 7714）
XinYongLIU, WenFangXU, JingDeWU. Synthesis of 4－Amino－5－furyl－2－yl－4H－1, 2, 4－triazole－3－thiol Derivatives as a Novel Class of Endothelin（ET） Receptor Antagonists[J]. 中国化学快报：英文版, 2003.
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