[Exploring the regulatory mechanism of <i>Sparassis latifolia</i> polysaccharides on hepatic glucose metabolism disorders in mice based on transcriptomics].
摘要
). Additionally, SLPs up-regulated p-FOXO1 protein expression level and down-regulated phosphoenolpyruvate carboxykinase (PEPCK) protein expression level. These results suggest that SLPs can effectively improve hepatic glucose metabolism disorders in mice induced by a high-fat diet combined with STZ by activating the PI3K/AKT/FOXO1 signaling pathway, involving the inhibition of key gluconeogenic enzymes and promotion of glucose utilization.
引用本文(GB/T 7714)
Er-Chen Yang, Feng-Ying Jia, Limin Zhang, 等. [Exploring the regulatory mechanism of <i>Sparassis latifolia</i> polysaccharides on hepatic glucose metabolism disorders in mice based on transcriptomics].[J]. PubMed, 2026.
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