Prospective Cohort Study of the Impact of Socioeconomic Status and Healthy Lifestyle on Cardiovascular Disease
摘要
Background Cardiovascular disease (CVD) is a global health problem, and it is not known whether socioeconomic status (SES) and healthy lifestyle (HL) have an impact on CVD onset. Objective To understand the relationship between SES, HL and CVD, and to provide a basis for the prevention and control of CVD in the population. Methods A multi-stage cluster random sampling method was employed to select 9 280 residents aged 18 and above from 12 counties and districts in Guizhou Province as the baseline sample in 2010. In 2016-2020 follow the cohort, face to face interview by unified training and qualified personnel, including basic situation, lifestyle (smoking, drinking, vegetables and vegetables, etc.), previous disease history, according to the survey was divided into CVD group (123) and non-CVD group (4 025) ; we used COX proportional hazard regression models were used to analyze the effect of SES and HL on CVD incidence. Additionally, an accelerated failure time model was utilized to assess the impact of different SES and HL at the time of CVD onset. Results After excluding baseline CVD patients, lost-to-follow-up and missing information, the valid sample size included in the analysis was 4 148, CVD onset 123, and the incidence density was 4.13 / 1 000 person-years. The results of multivariate analysis showed that compared with low SES (≤7 points), the risk of CVD in high SES (>7 points) decreased by 40.60% (HR=0.594, 95%CI=0.402-0.878). Compared with 6 HL populations, the population with 8 and 9 HL decreased by 44.40% (HR=0.556, 95%CI=0.320-0.968) and 49.20% (HR=0.508, 95%CI=0.284-0.912). Compared with the population in the low SES group and with HL ≤ 6 conditions, there was no statistically significant risk of CVD incidence in the population in the low SES group with HL of 7, 8, or ≥ 9 conditions (P>0.05) ; those with high SES (>7 points) and HL of 8 or 9 decreased CVD risk by 61.80% (HR=0.382, 95%CI=0.163-0.894) and 70.20% (HR=0.298, 95%CI=0.119-0.748, re