Association between Sleep Quality and Atherosclerosis among Population Aged 40-65 Years
摘要
Background Sleep quality is an important influence on arteriosclerosis (AS), but the category characteristics of sleep quality need to be further explored, and the association of each category with AS has not been clarified. Objective To explore the potential categories of sleep quality and analyze the association with AS, providing reference for refining individualized prevention strategies for AS. Methods The data of this study were obtained from the baseline survey of the "Follow-up Study of Sleep Characteristics and Chronic Diseases in the Middle-aged and Elderly Population in Guizhou Province", which was conducted from March to November 2022. Field questionnaires, physical examination and laboratory tests were conducted by uniformly trained investigators and professionals. Pittsburgh Sleep Quality Index (PSQI) was used to evaluate sleep quality problems, and latent class analysis (LCA) was performed using the scores of each dimension. Modified Poisson regression was used to analyze the association between sleep quality categories and AS. Stratification analysis was also conducted by gender, age and sleeping late. Results A total of 1 059 adults were included and a total of 558 patients with AS were detected, with a detection rate of 52.69%. Four sleep quality categories were identified via the LCA, including good sleep type (category 1, n=458), sleep deprivation with poor nighttime sleep quality (category 2, n=248), inefficient and insufficient sleep type (category 3, n=238), and multiple sleep problems type (category 4, n=115). The risk of AS was higher in the category 3 population than in category 1 (PR=1.14, 95%CI=1.00-1.30). Subgroup analyses revealed that in the female population, the risk of AS was higher in category 3 and category 4 compared to category 1, with PR=1.44 (95%CI=1.11-1.86) and 1.41 (95%CI=1.06-1.90). In addition, association between sleep quality categories and AS in the male population was not statistically significant. Compared