Anti-Neuronal Stress Effect of Tunisian Rosmarinus officinalis Extract
摘要
The present study is aimed to the effect of a Tunisian aromatic plant Rosmarinus officinalis extract on - a neuronal cell model - PC12 cells and on HSP47. The extract of R. officinalis and two pure compounds rosmarinic acid and carnosic acid promote markedly the neurite outgrowth of PC12 cells and enhanced the acetylcholinesterase activity same as NGF (neurite outgrowth factor). The investigation of phosphorylation marker illustrates that Rosemary extract treatment showed ERK1/2 phosphorylation same as NGF. Moreover, Rosmarinus extracts and its pure compounds have shown a stress recovery activity on HSP47.
引用本文（GB/T 7714）
Abdelfatteh El Omri, Junkyu Han, Ron Hashizume, 等. Anti-Neuronal Stress Effect of Tunisian Rosmarinus officinalis Extract[J]. 沙漠研究 : 日本沙漠学会誌, 2009.
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