蛋白质水凝胶三维微纳结构的飞秒激光增材-去除双模态加工
摘要
Objective Hydrogels are a class of polymeric soft materials with a three -dimensional (3D) crosslinked hydrophilic network structure, which possess the softness and high water content of natural tissues.They offer advantages over other synthetic biomaterials in simulating natural living tissues.In conventional approaches, ultraviolet (UV) -band single -photon beams are used for mode transitions in hydrogels.However, these approaches often fall short in terms of penetration depth and resolution, failing to meet the experimental expectations.In emerging methods, two -photon excitation of hydrogel materials using ultrafast lasers in the near -infrared band can improve the spatial and temporal resolution of hydrogels in various response states.However, these methods provide only single results for hydrogels and lack of multimodal processing capabilities, thereby limiting the application scenarios for hydrogels.In this study, we combine femtosecond laser direct -write micro/nano -processing with multiple optical response states of hydrogels.We