5个SNP突变位点对乌珠穆沁羊不同时期体重的影响
摘要
<p indent="0mm">The weight of sheep can directly reflect their growth and fattening speed and is also an important indicator for measuring the growth performance of meat sheep. This study focused on the Ujimqin sheep as the research object. One hundred SNP loci related to sheep body size were selected, and blood and weight data were collected from 252 Ujimqin sheep at different stages. MassARRAY genotyping technology was used to genotype these sheep strains at the selected SNP loci, and correlation analysis between weight data and genotyping results revealed that a total of 5 mutation sites were significantly correlated with the weight of Ujimqin sheep at different stages. Further protein structure prediction analysis of three missense mutation sites revealed that changes in the CDS of the three mutation sites resulted in varying degrees of changes in their protein tertiary structure, leading to individual weight differences. The aim of this study was to explore the characteristic loci related to the growth traits of Ujimqin sheep, providing a reference for the precise breeding of Ujimqin sheep in the future to promote the development of the Ujimqin sheep industry.