[Correlation of serum ferredoxin 1 and lipoic acid levels with severity of coronary artery disease].

Tong Wei、Yuchuan Ding、Jian Zhang、Jia Li、Hu Zhang、Pinfang Kang、Nana Zhang

2024PubMedBiochemistry, Genetics and Molecular Biology被引 2

摘要

OBJECTIVE: To analyze the correlation of copper death inducer ferredoxin 1 (FDX1) and lipoic acid (LA) with the occurrence and severity of coronary atherosclerosis and explore their roles in coronary heart disease (CHD). METHODS: mice using HE staining and observed collagen fiber deposition with Sirius red staining. Immunohistochemistry was used to detect the expression and distribution of FDX1 and LA in the aorta, and RT-PCR was performed to detect the expressions of FDX1, LIAS and ACO2 mRNAs in the myocardial tissues. RESULTS: < 0.05). CONCLUSION: Serum FDX1 and LA levels decrease with worsening of coronary artery lesions, and theirs expressions are correlated with coronary artery lesions induced by hyperlipidemia.

引用本文（GB/T 7714）

Tong Wei, Yuchuan Ding, Jian Zhang, 等. [Correlation of serum ferredoxin 1 and lipoic acid levels with severity of coronary artery disease].[J]. PubMed, 2024.

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DOI：https://doi.org/10.12122/j.issn.1673-4254.2024.02.13

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