基于LP01和LP11模式共存的单光纤光镊实现生物细胞多路捕获和操纵
摘要
Objective Currently, some biophotonic devices or cell -to -cell interactions and communications require the capture of particles, especially multiple particles.Since the invention of optical tweezers in 1986, optical tweezers have become an important tool that is widely used in the manipulation and study of cells, viruses, atoms, colloids, and other particles.remains stable when the fiber moves at a speed of about 14 m/s (Fig. 9).Conclusions In summary, a single -fiber optical tweezer for multiplexed alignment of multi -biological cells is proposed in this paper.The optical tweezer utilizes two different modes of fiber staggered splicing to make LP 01 and LP 11 modes coexist in the output optical field.Since the two mode beams have different propagation constants and exhibit different focused light fields, the capture of multi -biological cells in different directions can be achieved.Through the finite element analysis method, the optical field distribution of the optical fiber tweezer with 980 nm SMF and 1550 nm SMF being composite is simulated, and the force on Chlorella cells is analyzed.Finally, it is shown that optical tweezer can capture multiple Chlorella cells simultaneously in three directions and form a biological chain.The capture remains stable when the fiber travels at a speed of about 14 m/s.The simple structure of this optical fiber tweezer provides more possibilities for biosensing and direct detection of biosignals.