耳蜗毛细胞活动的神经动力学分析
摘要
To understand the neurodynamic mechanism of cochlear hair cell activity more profoundly, a hair cell model based on the Hodgkin-Huxley equation was established. Through numerical simulation, neurodynamic analysis of hair cell membrane potential, power, and energy consumption was performed. The results show that, when the sound frequency is in the range of 0.1~20 kHz, the attenuation of outer hair cells’ (OHCs) membrane potential will be lower than that of inner hair cells (IHCs), while the gains in power and energy consumption of OHCs will be much larger than those of IHCs. The low attenuation of OHC membrane potential and the high gains in power and energy consumption support the view that the OHC amplification is driven by electromotility. The study on membrane potential, power and energy consumption of cochlear hair cell contributes to the profound understanding of the neurodynamic properties of hair cell activity.