[Effect of chemokines CXCL9 and CXCL10 on bone erosion in patients with rheumatoid arthritis].

2021PubMedMedicine被引 4开放获取

摘要

OBJECTIVE: To detect the serum level of soluble chemokines CXCL9 and CXCL10 in patients with rheumatoid arthritis (RA), and to analyze their correlation with bone erosion, as well as the clinical significance in RA. METHODS: test, Spearman's rank correlation and Logistic regression were used for statistical analysis. RESULTS: < 0.05). CONCLUSION: Serum levels of CXCL9 and CXCL10 were remarkably elevated in patients with RA, and correlated with disease activities and occurrence of bone erosion. Chemokines CXCL9 and CXCL10 might be involved in the pathogenesis and bone destruction in RA.

引用本文（GB/T 7714）

Hua Zhong, Luo Xu, Mingxin Bai, 等. [Effect of chemokines CXCL9 and CXCL10 on bone erosion in patients with rheumatoid arthritis].[J]. PubMed, 2021.

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DOI：https://doi.org/10.19723/j.issn.1671-167x.2021.06.003

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