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[Molecular mechanism of zoledronic acid inhibiting angiogenesis by semi flexible binding with vascular endothelial growth factor conformation].

R J WangQingtong ZhaoYang YuYunlan ZhouShuke Wang

2021PubMedMedicine被引 1

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摘要

vascularization and expression of VEGF/HIF-1α. The binding site of ZOL with the conformation of VEGF was located in the hydrophobic region and hydrogen-bonding region of amino acids. Designing an antagonist targeting this site might potentially alleviate the effect of ZOL in inhibiting angiogenesis.

引用本文(GB/T 7714)

R J Wang, Qingtong Zhao, Yang Yu, 等. [Molecular mechanism of zoledronic acid inhibiting angiogenesis by semi flexible binding with vascular endothelial growth factor conformation].[J]. PubMed, 2021.

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DOI:https://doi.org/10.3760/cma.j.cn112144-20200729-00441

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