Association of ABO blood group and Plasmodium falciparum malaria in Dore Bafeno Area,Southern Ethiopia
摘要
Malaria PflPv Combo was also used to test the blood specimens for malaria.ABO blood groups were determined by agglutination test using ERYCLONE antisera.Data on socio-demographic characteristics and treatment status of the participants were also collected.Chi-square and ANOVA tests were used to assess the difference between frequencies and means,respectively.Results:Out of a total of 269 participants,178（66.2%） febrile patients were found to be infected with Plasmodium parasites,among which 146（54.3%）,28（10.4%）,and 4（1.5%） belonged to P.falciparum,P.vivax,and mixed infections,respectively.All febrile patients were also tested for ABO blood groups and 51.3%,23.5%,21.9%and 3.3%were found to be blood types of 0,A,B and AB,respectively.Both total malaria infection and P.falciparum infection showed significant association with blood types（P<0.05）.The proportion of A or B but not 0 phenotypes was higher（P<0.05） in individuals with P.falciparum as compared with non-infected individuals.The chance of having P.falciparum infection in patients with blood groups A,B and AB was 2.5,2.5 and 3.3times more than individuals showing blood 0 phenotypes,respectively.The mean P.falciparum malaria parasitemia for blood groups A,B,AB,and 0 were 3 744/μ L,1 805/ μ L,5 331/μ L,and1 515/μ L,respectively（P<0.01）.Conclusions:The present findings indicate that individuals of blood groups A,B and AB are more susceptible to P.f