Treatment of hepatocellular carcinoma： Steps forward butstill a long way to go
摘要
Hepatocellular carcinoma （HCC） is the fifth mostcommon malignancy and the third cause of tumorassociated deaths worldwide. HCC incidence ratesare increasing in many parts of the world includingdeveloping and developed countries. Potentiallycurative treatments for HCC are resection and livertransplantation, but these are only suitable for patientswith small tumors, meeting strict pre-defined criteria, orwell-compensated liver disease. Early diagnosis of HCCcan be achieved by surveillance of at-risk populations.For patients with non-resectable disease treatmentsmodalities include loco-ablative and systemic therapies.In this review we focus on treatment options in HCCand their allocation. Although significant research is inprogress, to this date, the results are unsatisfactorywith limited long-term survival. In the fight against thisdeadly disease, there is still a long way to go.