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EFFECT OF PARTIAL PRESSURE ON SOLUBILITY OF ISOFLURANE IN BLOOD

Xie、Lauber、Zbinden

1995中华医学杂志：英文版Medicine被引 2

摘要

The effect of partial pressure of isoflurane on its solubility in blood of different haematocrit was determined at different isoflurane partial pressures, using a syringe-flask method and gas chromatography with Mood from one donor. The silnbrany of isoflurane decreased with increasing blood haematocrit (39.5%, 51.9% and 61.9%) and isoflurane partial pressve from 1 MAC to 4 MAC. The solubility in 50% and 60% haematocrit blood at 2, 3 and 4 MAC was significantly different from the solubility in normal blood at 1 MAC (P<0.05). We conclude that the solution of isoflurane in blood (especially in high haematocrit blood) does not obey Henry’s law.

引用本文（GB/T 7714）