Primary Cutaneous Angioplasmocellular Hyperplasia
摘要
Primary cutaneous angioplasmocellular hyperplasia was first described by Gonzalez in 1995 as an asymptomatic, non-ulcerated, slightly umbilicated and violaceous nodule. To the best of our knowledge, only one additional case has been reportedsince the first two cases. We describe the first two patients in Taiwan. A 39-year-old man had a painless, erythematous, approximately 1-cm nodule with a dark red halo on the lower back. A 35-year-old woman presented with a friable nodule that bled easily and had peripheral erythema on the upper chest wall. Neither patient had a history of local trauma or previous lesions. Histopathologic examination of the excisional biopsy specimen from both showed hyperkeratosis and acanthosis of the epidennis. In the upper dermis, there was abundant capillary-like proliferation of blood vessels surrounded by abundant plasma cell infiltrates. It is essential to differentiate this entity from pyogenic granuloma, Kaposi's sarcoma, epithelioid hemangioendothelioma, arthropod bite reactions, and acral pseudolymphomatous angiokeratoma.