CARCINOGENICITY OF FUSARIN C ISOLATED FROM FUSARIUM MONILIFORME
摘要
Fusarium monilljorme, a fungus of established carcinogenic potential, is one of the most common fungal contaminants of maize, millet and other grains in Linxian County, China. Fusarin C, a major product of F. monilljorme grown on corn in the laboratory, is mutagenic in Salmonella tester strains and in V79 cells. Fusarin C showed several characteristics of malignant transformation including the implantation of the rat esophageal epithelial cell line (RE ?525) in nude mice. The present work demonstrated that fusarin C can induce esophageal and forestomach carcinomas in DBA mice and Wistar rats, and thus the experimental results substantiated further the carcinogenicity of fusarin C.
引用本文(GB/T 7714)
李铭新, 蒋原宙, Bjeldanes. CARCINOGENICITY OF FUSARIN C ISOLATED FROM FUSARIUM MONILIFORME[J]. Acta Scientiarum Naturalium Universitatis Sunyatseni, 1990.
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