Benign Symmetric Lipomatosis
摘要
Background: Madelung's disease, benign symmetric lipomatosis, is a rare proliferative disease predominantly seen in middle-aged male patients. The disorder is characterized by multiple symmetrical, painless deposits of non-encapsulated fat around the neck, upper arms and upper part of the thorax. No clear etiology has been recognized while a close correlation to alcohol and metabolic disturbances has been observed. Aim and Objectives: To evaluate the clinicopathologic, morphologic and biochemical findings in this disease, we present and discuss various factors in this disease of 5 cases and give a survey of the literature. Materials and Methods: Five patients with benign symmetric lipomatosis were reviewed. All were male, aged 38 to 73 years, with a history of disease ranging from 6 months to 7 years. Patients usually complain of their cosmetic appearance, limited range of motion of the neck, difficulty in swallowing and compression of the airway. We performed the surgical excision via lipectomy with or without liposuction in all patients for the neck tumors. Results: The mean follow-up period was 88.6 months. The functional results were satisfactory in all patients. A recurrence was observed in one of our patients six months after the operation. Severe complications were not observed. Conclusions: According to our experience, surgical removal of lipomatous tissues in BSL can yield satisfactory functional and cosmetic results.