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Influence of interleukin polymorphisms on development of gastric cancer and peptic ulcer

MitsushigeSugimotoYoshio YoshioYamaokaTakahisaFuruta

2010Acta Scientiarum Naturalium Universitatis SunyatseniMedicine被引 3

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摘要

Pro-inflammatory cytokines are produced in the gastric mucosa by inflammatory cells activated by chronic Helicobacter pylori (H. pylori) infection. Polymorphisms of these cytokine genes are associated with individual differences in gastric mucosal cytokine mRNA level, which result in differences in gastric mucosal inflammation, acid inhibition and gastroduodenal disease risk in response to H. pylori infection. Although polymorphisms of interleukin (IL)-1B, IL-1RN and TNF-A have been reported to relate well ...

引用本文(GB/T 7714)

Mitsushige, Sugimoto, Yoshio Yoshio, 等. Influence of interleukin polymorphisms on development of gastric cancer and peptic ulcer[J]. Acta Scientiarum Naturalium Universitatis Sunyatseni, 2010.

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