BCNU/PLGA microspheres： a promising strategy for the treatment of gliomas in mice

Tong-ming、Zhu、Yiwen、Shen、Qisheng、Tang Tang、Luping、Chen

2014Acta Scientiarum Naturalium Universitatis SunyatseniMaterials Science被引 5

摘要

0.05),with the ratio of Bax/Bcl-2 increased.For MGMT protein expression,no statistically significant change was found in treated group(P>0.05).Conclusions:Local implantation of BCNU/PLGA microspheres improved the survival quality and time of GL261 glioma-bearing mice significantly,inhibited the tumor proliferation,induced more cell apoptosis,and did not increase the chemotherapy resistance.

引用本文（GB/T 7714）

Tong-ming, Zhu, Yiwen, 等. BCNU/PLGA microspheres： a promising strategy for the treatment of gliomas in mice[J]. Acta Scientiarum Naturalium Universitatis Sunyatseni, 2014.

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