Ikaros in B cell development and function

Maclean、Sellars、Philippe、Kastner、Susan Susan、Chan

2011世界生物化学杂志：英文版（电子版）Medicine被引 1

摘要

The zinc finger transcription factor,Ikaros,is a central regulator of hematopoiesis.It is required for the development of the earliest B cell progenitors and at later stages for VDJ recombination and B cell receptor expression.Mature B cells rely on Ikaros to set the activation threshold for various stimuli,and to choose the correct antibody isotype during class switch recombination.Thus,Ikaros contributes to nearly every level of B cell differentiation and function.

引用本文（GB/T 7714）

Maclean, Sellars, Philippe, 等. Ikaros in B cell development and function[J]. 世界生物化学杂志：英文版（电子版）, 2011.

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