Effect of SNC19/ST14gene overexpression on invasion of colorectal cancer cells

Kefeng、Ding Ding、Lifeng、 Sun、Wei-ting、Ge Ge、Han-guang、Hu

2005Acta Scientiarum Naturalium Universitatis SunyatseniBiochemistry, Genetics and Molecular Biology被引 2

摘要

AIM: To study the effect of SNC19/ST14gene overexpression on invasion in vitro of colorectal cancer cells.METHODS: The adhesion of SNC19/ST14gene-transfected cells to ECM was measured by MTT assay. The cell movement was evaluated by wound healing assay. Cell invasion and migration were determined by invasion assay in vitro.RESULTS: SNC19/ST14 gene overexpression could enhance invasion of colorectal cancer cells in vitro significantly and influence early cell adherence to ECM,but could not change cell movement significantly.CONCLUSION: SNC19/ST14 gene overexpression increases the local invasion of colorectal cancer cells in vitro.

引用本文（GB/T 7714）

Kefeng, Ding Ding, Lifeng, 等. Effect of SNC19/ST14gene overexpression on invasion of colorectal cancer cells[J]. Acta Scientiarum Naturalium Universitatis Sunyatseni, 2005.

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