拓扑结构高分子的高效“点击”合成
摘要
Topological macromolecules including branched macromolecules such as starlike, dendritic and cyclic and muticyclic macromolecules have many unique properties different from linear counterparts, and thus are new polymeric materials with potential applications in such areas as nanotechnology, biomedicines and pharmaceutics. However, their tedious synthesis is the inherent barrier preventing them from real applications. Click reactions, which are fast, selective under mild reaction conditions and create only inoffensive by-products, have greatly advanced the synthesis methodologies of topological polymers. In this review, we briefly discuss the applications of click reactions including copper catalyzed azide-alkyne cycloaddition (CuAAC), thiol-yne/ene, amine-acrylate, Diels-Alder cycloaddition reactions in synthesis of topological polymers. The future directions in this area are also discussed.