Lymphoid tyrosine phosphatase R620W variant and inflammatory bowel disease in Tunisia

Imen、Sfar、Walid Walid、Ben、Aleya、Leïla、Mouelhi、Houda

2010Acta Scientiarum Naturalium Universitatis SunyatseniBiochemistry, Genetics and Molecular Biology被引 4

摘要

AIM:To assess the possible association between PTPN22(R620W) gene polymorphism and inflammatory bowel disease(IBD).METHODS:One hundred and sixty-four patients with IBD 105 Crohn's disease(CD) and 59 ulcerative colitis(UC) and 100 healthy controls were recruited.Genotyping of the PTPN22 gene 1858C→T polymorphism was performed by restriction fragment length polymorphism-polymerase chain reaction with Rsa Ⅰ digestion.RESULTS:The genotypic and allelic frequencies of(R620W) PTPN22 gene polymorphism reveal a sign...

引用本文（GB/T 7714）

Imen, Sfar, Walid Walid, 等. Lymphoid tyrosine phosphatase R620W variant and inflammatory bowel disease in Tunisia[J]. Acta Scientiarum Naturalium Universitatis Sunyatseni, 2010.

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