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Histopathological and molecular prognostic markers in medulloblastoma: c-myc, N-myc, TrkC, and anaplasia

EberhartCGKratzJWangYSummersKStearnsDCohenKChi V. DangBurgerPC

2004中国神经肿瘤杂志Medicine被引 16

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摘要

Several molecular and histopathologieal prognostic markers have been proposed for the therapeutic stratification of meduUoblastoma patients. Amplification of the c-mye oneogene, elevated levels of c-mye mRNA, or tumor anaplasia have been associated with worse clinical outcomes. In contrast, high TrkC mRNA expression generally presages longer survival. The goal of this study was to evaluate the

引用本文(GB/T 7714)

EberhartCG, KratzJ, WangY, 等. Histopathological and molecular prognostic markers in medulloblastoma: c-myc, N-myc, TrkC, and anaplasia[J]. 中国神经肿瘤杂志, 2004.

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