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[Construction of apoptosis-stimulating of p53 protein 2 gene knockout mice and its effect on diethylnitrosamine-induced liver cancer].

Xin LiuBuxin KouMengyin ChaiD X Chen

2020PubMedBiochemistry, Genetics and Molecular Biology被引 1开放获取

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摘要

ASPP2 knockout mice were successfully constructed based on the CRISPR/Cas9 system. The success rate of DEN-induced liver cancer model of ASPP2 knockout mice was significantly higher than that of the wild-type mice.

引用本文(GB/T 7714)

Xin Liu, Buxin Kou, Mengyin Chai, 等. [Construction of apoptosis-stimulating of p53 protein 2 gene knockout mice and its effect on diethylnitrosamine-induced liver cancer].[J]. PubMed, 2020.

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DOI:https://doi.org/10.3760/cma.j.cn501113-20190728-00274

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