Lentiviral vectors in cancer immunotherapy

2008国际外科学杂志Biochemistry, Genetics and Molecular Biology被引 23

摘要

Lentiviral vectors can transduce a wide range of different cell types.It can transduce not only dividing cells but also nondividing cells.It can be the immunotherapy tool for cancer therapy.Lentiviral yeators have several advantages,amongst which long-term expression,low toxicity,high capacity and low antivector immunity,they will play an important role and will attract more and more interest as an immunotherapeutic.Here,we discussed the clinical application and safety of the lentiviruses encoding tumor-associated antigen(TAA). Key words: lentivirus; vector; vaccine; cancer; immunotherapy

引用本文（GB/T 7714）

Shan Lin, Bing Wang, Lie Wang. Lentiviral vectors in cancer immunotherapy[J]. 国际外科学杂志, 2008.

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DOI：https://doi.org/10.3760/cma.j.issn.1673-4203.2008.03.011

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