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[Expressions and Significance of PTEN and LKB1 in Non-small Cell Lung Cancer].

Li Yang、Ying Li、Hui Yang、Ping Wang

2016PubMedBiochemistry, Genetics and Molecular Biology被引 2

摘要

OBJECTIVES: To analyze the correlation between the expression of PTEN and LKB1 in non-small cell lung cancer (NSCLC). METHODS: Paraffin blocks of 74 cases of NSCLC patients were collected, and the expression of LKB1 and PTEN were detected by immunohistochemistry. The clinical related index and the correlation with the expression of PTEN and LKB1 were analyzed to explore the expression clinical significance of them. RESULTS: =0.003). Patients with PTEN and LKB1 positive showed more LNM and/or invasion than those with them negative. CONCLUSIONS: The expression of PTEN and LKB1 may be related to the occurrence and progression of NSCLC, and may have a synergistic effect, and it can be used as a judgment of the prognosis of NSCLC.

引用本文（GB/T 7714）