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[Recent Research Advances on Signaling Pathway in B-cell Malignancy - Review].

Xiuli ChenZhenshu Xu

2018PubMedMedicine被引 1

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摘要

B-cell malignancy, a kind of malignant tumor of blood system, is characterized by heterogeneity and complexity of the pathogenesis. In this review, the recent advances of studies on B-cell malignancy and signaling pathways are briefly summarized. This review focuses on the role of signaling pathways, especially the NF-κ B, Wnt, PI3K/Akt, Notch and JAK/STAT signaling pathway in the occurrence and development of B-cell malignancy, and discussed the influence of signaling pathways on the invasiveness and drug resistance of B-cell malignancy, and the clinical application of signaling pathway inhibitors.

引用本文(GB/T 7714)

Xiuli Chen, Zhenshu Xu. [Recent Research Advances on Signaling Pathway in B-cell Malignancy - Review].[J]. PubMed, 2018.

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DOI:https://doi.org/10.7534/j.issn.1009-2137.2018.01.053

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