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[The Effect of Sodium Ferulate in Experimental Pulmonary Fibrosis via NALP3 Inflammasome].

Ju KuangXiaolin WeiMin Xie

2017PubMedBiochemistry, Genetics and Molecular Biology被引 5

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摘要

OBJECTIVE: To investigate the activation of NALP3 inflammasome in the process of experimental pulmonary fibrosis (PF), and evaluate the effect of sodium ferulate (SF) in the relationship of NALP3 and PF. METHODS: in fibroblast as well. Meanwhile, IL-1β content in lung tissue and cell supernatant was measured by ELISA. RESULTS: <0.05) compared with those of H₂O₂ group. CONCLUSION: Sodium ferulate may suppress oxidative stress mediated NALP3 activation to inhibit fibroblast activation in the anti-fibrosis effect.

引用本文(GB/T 7714)

Ju Kuang, Xiaolin Wei, Min Xie. [The Effect of Sodium Ferulate in Experimental Pulmonary Fibrosis via NALP3 Inflammasome].[J]. PubMed, 2017.

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