[Expression of H3.3 G34W mutant-specific antibody in giant cell tumors of bone and its diagnostic value].

Xiaoyong Wang、Nina Wu、R S Zhang、Xiumei Wei、Ronghao Ji、H H、Xiaojun Zhou、Qinchun Rao

2020PubMedMedicine被引 1

摘要

H3.3 G34W mutant-specific antibody is a highly sensitive and specific marker for GCTB and helpful for the diagnosis of GCTB and its variants. The limitation of this antibody is that as a mall number of GCTB harbor G34 mutation other than G34W, and thus that cannot be detected. The incidental expression of H3.3 G34W mutant protein in osteosarcoma could be a potential diagnostic dilemma, and the results of H3.3 G34W IHC staining needs careful interpretation.

引用本文（GB/T 7714）

Xiaoyong Wang, Nina Wu, R S Zhang, 等. [Expression of H3.3 G34W mutant-specific antibody in giant cell tumors of bone and its diagnostic value].[J]. PubMed, 2020.

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DOI：https://doi.org/10.3760/cma.j.issn.0529-5807.2020.02.003

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