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[The relationship between adherens junction and tight junction and clinical symptoms in patients with diarrhea predominant irritable bowel syndrome].

M ZhangC Y ChenYuming HuBin Lü

2020PubMedMedicine被引 3

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摘要

Intercellular ultrastructure alterations well as cecal β-catenin and E-cadherin protein expression decrease and are associated with high abdominal pain score in IBS-D patients and hypersensitivity rats. β-catenin is further associated with prolonged duration of symptoms in IBS-D patients. The expression of E-cadherin and β-catenin may play a vital role in visceral sensitivity and intestinal barrier dysfunction in IBS-D.

引用本文(GB/T 7714)

M Zhang, C Y Chen, Yuming Hu, 等. [The relationship between adherens junction and tight junction and clinical symptoms in patients with diarrhea predominant irritable bowel syndrome].[J]. PubMed, 2020.

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DOI:https://doi.org/10.3760/cma.j.issn.0578-1426.2020.01.007

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