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[Effect of glucagon-like peptide 1 receptor agonists on body fat redistribution and muscle mass in overweight and obese type 2 diabetic patients].

Yudan ZhangShiqun LiuCunxia FanYanmei ZengJimin LiCuihua XieYaoming XueMeiping Guan

2019PubMedMedicine被引 5

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摘要

OBJECTIVE: To investigate the effect of glucagon-like peptide 1 receptor agonists (GLP-1RAs) on body fat redistribution and muscle mass in overweight/obese patients with type 2 diabetes (T2DM). METHODS: =27). All the patients received treatment with GLP-1RAs (Exenatide or Liraglutide) for 3.0 to 29.0 weeks (mean 8.9 weeks), and their blood glucose, HbA1c and serum lipids were analyzed. For each patient, the fat and muscle masses were analyzed using a human body composition analyzer (JAWON-IOI353, Korea) before and after GLP-1RAs treatment. RESULTS: < 0.05). CONCLUSIONS: GLP-1RAs treatment can significantly lower BMI and improve body fat distribution in obese patients with T2DM, especially in patients with a greater BMI.

引用本文(GB/T 7714)

Yudan Zhang, Shiqun Liu, Cunxia Fan, 等. [Effect of glucagon-like peptide 1 receptor agonists on body fat redistribution and muscle mass in overweight and obese type 2 diabetic patients].[J]. PubMed, 2019.

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DOI:https://doi.org/10.12122/j.issn.1673-4254.2019.04.11

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