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Intramolecular Aldol Condensation Route to 14α,17α-Propanoestradiols and 14α,17α-Ethano-17a-homoestradiols

James R. BullL. M. STEERKrzysztof Jaworski

1994SynlettBiochemistry, Genetics and Molecular Biology被引 2

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摘要

All articles of this category 17β-Acetoxy-3-methoxy-20-oxo-19-nor-17α-pregna-1,3, 5(10)-triene-14-carbaldehyde undergoes intramolecular aldol condensation to give 14α,17α-bridged intermediates which are converted into 14α,17α-propano and 14α,17α-ethano-17a-homo analogues of estradiol.

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James R. Bull, L. M. STEER, Krzysztof Jaworski. Intramolecular Aldol Condensation Route to 14α,17α-Propanoestradiols and 14α,17α-Ethano-17a-homoestradiols[J]. Synlett, 1994.

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DOI:https://doi.org/10.1055/s-1994-22979

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