电泳技术在纳米颗粒分离中的应用
摘要
Synthetic nanoparticles often bear wide distribution in size and shape. However, it is critical to have nanoparticles with the lowest size and shape dispersion possible in many experiments for their unique size- and/or shape-dependent physiochemical properties. Therefore, quick and handy separation methods of nanoparticles have brought considerable attention in many scientific areas recently. Electrophoresis has been extensively used in the separation and purification of biological molecules such as nucleic acids and proteins with a remarkable resolution. The charged nanoparticles are very close in size to protein complexes, organelles and microorganisms, and share similarity in motion behavior with biological molecules in an electric field. It is a new idea to use electrophoresis technology for nanoparticles’ identification, separation and purification, which has achieved favorable results. This review presents recent advances in the separation of nanoparticles by agarose gel electrophoresis, capillary electrophoresis and some other electrophoretic techniques.