[Study on preparation of the inclusion compound of curcumin with beta-cyclodextrin].

Gang Han、Jianhua Xu、Weina Li、Chunling Ning

2004PubMedPharmacology, Toxicology and Pharmaceutics被引 5

摘要

OBJECTIVE: The inclusion compound of curcumin with, beta-CD was preparated to increase the solubility and bioavaliability of curcumin. METHODS: Prepare inclusion compound was studied with orthogonal design. The inclusion compound was verified with fluorometry, TLC, and phase solubility. RESULT: The best way to prepare inclusion compound are as follows: the molar ratio between curcumin and, beta-CD is 1:1, temperture is 40 degrees C, reaction time is 2 h. CONCLUSION: Solubility of inclusion compound is 10 times than curcumin.

引用本文（GB/T 7714）

Gang Han, Jianhua Xu, Weina Li, 等. [Study on preparation of the inclusion compound of curcumin with beta-cyclodextrin].[J]. PubMed, 2004.

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