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[Action of protein phosphatase-1 on Tat-dependent HIV-1 transcription and its related inhibitors].

Jun WangXinyong Liu

2009PubMedBiochemistry, Genetics and Molecular Biology被引 1

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摘要

Host cell protein phosphatase-1 (PP1) is an important regulator of human immunodeficiency virus-1 (HIV-1) transcription. PP1 is involved in the regulation of HIV-1 transcription, and dephosphorylates RNA polymerase II C-terminal domain (RNAPII CTD) or CycT1-dependent kinase 9 (CDK9) to increase Tat-dependent HIV-1 transcription. In this review, we discuss the action of PP1 in Tat-induced HIV-1 transcription and related to PP1 inhibitors.

引用本文(GB/T 7714)

Jun Wang, Xinyong Liu. [Action of protein phosphatase-1 on Tat-dependent HIV-1 transcription and its related inhibitors].[J]. PubMed, 2009.

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