[A study of CGRP receptor and its effect on the growth of human pancreatic carcinoma cells].
摘要
In the present studies the calcitonin gene-related peptide (CGRP) receptors were characterized by radioligand analysis and the effect of CGRP and CGRP receptor antagonist on the growth of human pancreatic carcinoma cells (PU-PAN-1) was determined by 3H-TdR incorporation assay. The results indicated that human pancreatic carcinoma cells possess distinct CGRP receptors. CGRP stimulated the growth of PU-PAN-1 tumor cells, and CGRP receptor antagonist CGRP8-37 inhibited these effects. These results suggests that CGRP receptors may play an important role in the growth of human pancreatic carcinoma cells (PU-PAN-1).
引用本文（GB/T 7714）
Zhishang Zhou. [A study of CGRP receptor and its effect on the growth of human pancreatic carcinoma cells].[J]. PubMed, 1993.
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