[Protective effect of berberine on isolated perfused heart in heart failure].
摘要
OBJECTIVE: To examine the protective action of berberine against the development of heart failure. METHODS: Wister rats were divided into two groups. The Langendorff perfusion of isolated heart was performed and Verapamil was used to bring about acute heart failure. The experiment group was given berberine (10(-6) mol/L) before the use of Verapamil, but the control group was not given the berberine. A comparison was made on the degree of heart failure between the two group. RESULTS: The degree of heart failure in the experiment group was significantly less severe than that in the control group (P < 0.001). CONCLUSION: Berberine has the protective action against to the development of heart failure.
引用本文（GB/T 7714）
Ziqi Zhou, Jian Xu, Tsuo‐Hung Lan. [Protective effect of berberine on isolated perfused heart in heart failure].[J]. PubMed, 2001.
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