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[Hepatitis B virus core protein as an epitope vaccine carrier: a review].

Ying YinJunjie XuWei Chen

2010PubMedMedicine被引 2

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摘要

Hepatitis B virus core (HBc) proteins have been used as carrier for foreign epitopes since the 1980s. They could self-assemble into icosahedral particles. Foreign epitopes could be inserted into HBc protein in various protein regions, including the N- or C-terminal and the major immunodominant region (MIR). The factors relevant in the design of HBc particles for vaccine purpose are summarized in this review.

引用本文(GB/T 7714)

Ying Yin, Junjie Xu, Wei Chen. [Hepatitis B virus core protein as an epitope vaccine carrier: a review].[J]. PubMed, 2010.

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