[A study on the effect of emodin on smooth muscle cell proliferation].
摘要
By using smooth muscle cell (SMC) culture in vitro and H3-TdR incorporation technique, we tested the effect of Emodin on SMC proliferation in three groups: (1) Normal rabbit iliac artery, (2) atherosclerotic rabbit iliac artery, (3) atherosclerotic rabbit iliac artery after PTA. These data indicated: Emodin has antiproliferative effect on SMC, which is dose dependent; it blocks the transition of SMC cycle from G0 to S. In PTA group it exerts a more significant proliferative effect than in the normal one. This is a the first report of Emodin's effect on SMC proliferation, it implies that the drug may be used clinically to prevent restenosis after PTCA.
引用本文（GB/T 7714）
Dongze Guo, Chang-Rong Xu, Y Chen. [A study on the effect of emodin on smooth muscle cell proliferation].[J]. PubMed, 1996.
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