[Comparison of the clinical effect of complex transplantation with heterogenetic acellular dermal M(ADM) AND allogeneic ADM].
摘要
OBJECTIVE: To explore the short-term clinical effects of complex transplantation among the acellular dermal matrix(ADM) of heterogenic or allogeneic and autogenic split on the burnt wound as to find out a permanent substitution for the treatment on full skin thickness defect without scar. METHODS: Two kinds of ADM were used on the 18 patients with full thickness burn wound through complex transplantation with autogenic splits. The patients with medial-thickness autograft was used as control group. Survival rate was obtained 2 weeks after operation; contraction rate and the scores of Vancouver burn scale were obtained 8 weeks after operation. RESULTS: No significant difference was observed in survival rate among the three groups 2 weeks after operation(P > 0. 05); no significant difference was observed in contraction rate of autografts and scores of Vancouver burn scale among the three groups 8 weeks after operation (P > 0. 05). CONCLUSION ADM of heterogenic and ADM of allogeneic have similar effect on the reconstruction of skin, so the piglet ADM made in this way could be used as a substitution.