[Cerebral venous thrombosis and factor V Leiden mutation].
摘要
OBJECTIVE: To investigate the relationship between factor V Leiden mutation and cerebral venous thrombosis in China. METHODS: 20 patients and 50 controls of Chinese origin were studied by polymerase chain reaction followed by Mnl I restriction enzyme analysis. RESULTS: The PCR products of all the people supervised were digested to three segments with the length of 37 bp, 67 bp, and 116 bp. No factor V Leiden mutation was found in any subjects. CONCLUSION: Factor V Leiden mutation is not a crucial risk factor of cerebral venous thrombosis.
引用本文(GB/T 7714)
Qiang Meng, Chuanqiang Pu. [Cerebral venous thrombosis and factor V Leiden mutation].[J]. PubMed, 2002.
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