[Effects of p,p'-DDE on expression of inhibin B in sertoli cells of rats].

Chong Wang、Hongkai Liu、Hongwei Zhang、Kedi Yang

2009PubMedBiochemistry, Genetics and Molecular Biology被引 1

摘要

OBJECTIVE: To study the effects of p,p'-DDE on the expression of inhibin B in sertoli cells of rats. METHODS: Sertoli cells were separated and cultured from testicular tissue of rats, and ensured the dose of test materials by MTT test, and RT-PCR were measured on the changes of inhibin B expression. RESULTS: The results indicated that there was high difference in middle and high dose groups in comparison with control group (P < 0.05), and there were statistical significance in comparison with low dose group, and the gray scale of inhibin B decreased with the increase dose of p,p'-DDE. CONCLUSION: The results indicated that p,p'-DDE could inhibit the expression of inhibin B.

引用本文（GB/T 7714）

Chong Wang, Hongkai Liu, Hongwei Zhang, 等. [Effects of p,p'-DDE on expression of inhibin B in sertoli cells of rats].[J]. PubMed, 2009.

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