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[Pure red cell aplasia after allogeneic peripheral blood stem cell transplantation: a case report and literature review].

Li C、Mei Han、Sizhou Feng

1999PubMedMedicine被引 1

摘要

OBJECTIVE: To report a case of post-allogeneic peripheral blood stem cell transplantation (allo-PBSCT) pure red cell aplasia(PRCA) and the treatment outcome. METHODS: A patient with acute non-lymphoblastic leukemia(M2a) was treated with allo-PBSCT. His post-PBSCT PRCA was treated with plasmapheresis(2-3 times weekly) and Epo(3,000 U/day, subcutaneously). RESULTS: Reticulocyte count (Ret) recovered to 0.01 at day +131 and hemoglobin reached 110 g/L at day +154. Erythroid cells in the bone marrow recovered to 0.25, and BFU-E and CFU-E within normal range. This normalized hematopoiesis remained for over 5 months after the cessation of Epo. CONCLUSION: Post allo-PBSCT PRCA can be successfully treated with plasma exchange and Epo.

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