[Effects of ferulic acid on bFGF-treated PC12 cells].

Lian-Feng Lin、Fei Xiao、Yongchang Lai、Ju-nian Su、Huanmin Luo

2011PubMedNeuroscience被引 1

摘要

OBJECTIVE: To explore the effect and mechanism of ferulic acid on differentiation in bFGF-treated PC12 cells. METHODS: The length of neurite outgrowth and the percentage of PC12 cells induced in the presence of 0 ng/mL or 1 ng/mL bFGF were assayed. RESULTS: Compared with that of control group,ferulic acid could enhance the differentiation effect of bFGF (1 ng/mL) in PC12 cells (P < 0.01) and the enhancing effect could be blocked by the specific MAPK kinase inhibitor, PD98059. CONCLUSION: Ferulic acid potentiates neurite outgrowth in bFGF-treated PC12 cells by MAPK-dependent signaling pathway.

引用本文（GB/T 7714）

Lian-Feng Lin, Fei Xiao, Yongchang Lai, 等. [Effects of ferulic acid on bFGF-treated PC12 cells].[J]. PubMed, 2011.

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